Sulf1 ovary
Web7 Jan 2011 · Abstract. Background: SULF1 (sulfatase 1) selectively removes the 6-O-sulphate group from heparan sulfate, changing the binding sites for extracellular growth … Web1 Apr 2024 · Sulf1 is a TGF-beta1-responsive gene both in vitro and in vivo and may function as a negative regulator of TGF-beta1-induced fibrogenesis modulates signaling …
Sulf1 ovary
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WebDownload scientific diagram HSulf-1 expression in ovarian cell lines and in OV207 treated with 5-aza-dC and TSA. (a) RT–PCR products of HSulf-1 and control GAPDH were visualized by agarose gel ... Web7 Jan 2011 · Background: SULF1 (sulfatase 1) selectively removes the 6-O-sulphate group from heparan sulfate, changing the binding sites for extracellular growth factors. SULF1 expression has been reported to be decreased in various cancers, including ovarian cancer. We hypothesized that single nucleotide polymorphisms (SNPs) of SULF1 would impact …
Web1 May 2024 · Six candidate genes had been screened out including one previously validated gene SULF1 and five novel genes ZNF587B, TADA1, SEMA4G, POTEC and USP17L20. … Web(A-D) Light microscopy images of an intact pair of ovaries from wild-type (A and B) and wdp; Sulf1 double mutant (C and D) females. The ovaries were dissected from young (day-3; A and C) and old ...
Web21 May 2011 · SULF1 down-regulation has been described in human primary tumorous samples and/or cell lines in ovarian cancer [8-10], hepatocellular carcinoma , breast cancer , gastric cancer , kidney cancer , prostatic stromal cells from benign prostatic hyperplasia samples and head and neck squamous cell carcinoma (SCCHN) cell lines . Web1 Mar 2012 · SULF1 is an endosulfatase able to cleave specific 6-O sulfate groups within the heparan chains. This action can modulate signaling processes, modulating the effects of …
Web23 Oct 2006 · In addition, research by other laboratories has shown that Sulf1 activity in ovarian cells decreases Noggin (a BMP antagonist) binding to the cell surface and hence enhances the activity of BMPs (Viviano et al., 2004), …
WebOvary OVARY - Expression summary The protein expression bar, with the units none (n), low (l), medium (m) and high (h), is based on a best estimate of the "true" protein expression … dst keeps crashingWebSULF1. On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). … dstl annual reportWebThis study aims to examine the role of polymorphisms in sulfatase 1 (SULF1) in platinum resistance and survival in advanced epithelial ovarian cancer (EOC) patients. We … commercial waterproofingWeb1 May 2024 · Lots of studies had demonstrated that SULF1 was associated with platinum resistance. Down-regulation of SULF1 in ovarian cancer cells led to an attenuation of … commercial waterproofing inc west chester paWebTo test whether the two CAF subtypes were a general feature of ovarian cancer stroma, we analyzed the gene expression dataset generated by Leung et al. (2014), who used laser … dstl apprenticeships 2022Web7 Jan 2011 · In ovarian cancer, decreased expression of SULF1 and its correlation with decreased sensitivity to cisplatin (a standard chemotherapeutic agent) were also reported [12,15]. Loss of heterozygosity or hypermethylation of the promoter region has been suggested as potential mechanisms for SULF1 down-regulation in ovarian cancer [ 14 ]. commercial waterproofing companies ohioWeb10 Dec 2013 · The survey about polymorphisms of SULF1 gene, for the first time was performed by Han et al. who genotyped five common single nucleotide polymorphisms (SNPs) in SULF1 gene to evaluate associations between these functional SULF1 SNPs and the risk of ovarian cancer . They found that some of the SULF1 gene SNPs can have one … commercial waterproofing st louis