Cst foxo3a

WebFoxO3a (75D8) Rabbit mAb detects exogenous and endogenous levels of total FoxO3a protein. The antibody does not detect the exogenously expressed family members FoxO4 or FoxO1. Species Reactivity: Human, Mouse, Rat, Monkey Source / Purification WebSignaling Technology (CST) allows the researcher to specifically inhibit FoxO3a expression using RNA interfer-ence, a method whereby gene expression can be selectively silenced …

Resveratrol attenuates radiation enteritis through the SIRT1/FOXO3a …

WebApr 22, 2024 · FOXO3a is a key target of AKT, and AKT phosphorylates FOXO3a at Thr32 residues, resulting in a decreased expression of FOXO3a. We then investigated whether … WebJul 17, 2003 · FOXO3a was cleaved in vitro by caspase-3-like proteases at the consensus sequence DELD304A, releasing the N-terminal DNA-binding domain of FOXO3a from its … philosophy quotes about mental health https://oceanasiatravel.com

Adjudin synergizes with paclitaxel and inhibits cell growth and ...

Gopinath et al. (2014) demonstrate a functional requirement for FOXO3 as a regulator of Notch signaling pathway (an essential regulator of quiescence in adult stem cells) in the self-renewal of stem cells during muscle regeneration. It is thought that FOXO3a is also involved in protection from oxidative stress by upregulating antioxidants such as catalase and MnSOD. Ron DePinho's group generated Foxo3 knockout mic… WebApr 11, 2024 · Nutrition during the developmental stages has long-term effects on adult physiology, disease and lifespan, and is termed nutritional programming. However, the underlying molecular mechanisms of nutritional programming are not yet well understood. In this study, we showed that developmental diets could regulate the lifespan of adult … WebIOP1抗体、Lamin A/C抗体、LC3BⅠ抗体、LC3BⅡ抗体、FOXO3a抗体、p62抗体、ATG5、ATG12抗体、GAPDH抗体均购自美国CST公司。荧光定量PCR仪型号为LightCycler 480，购自瑞士罗氏公司。 1.2方法. 1.2.1细胞培养 HEK293T在37 ℃，5% CO2培养箱中用含10% FBS的高糖DMEM培养基培养。 t shirt printing cedar city utah

The FOXO3-FOXM1 axis: A key cancer drug target and a …

Category:SignalSilence FoxO3a siRNA I - Cell Signaling Technology

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Cst foxo3a

Elucidating the role of the FoxO3a transcription factor in the …

WebFox03a Antibody 可检测 Fox03a 总蛋白的外源和内源水平。 该抗体不检测外源表达的家族成员 Fox04 或 Fox01。 该抗体与牛血清（包括 BSA）的变性组分发生反应。 物种反应性： 人, 猴 基于 100% 序列同源性预测发生 … WebDec 1, 2016 · For example, FoxO3a activates FasL transcription, the ligand for the Fas-dependent cell death pathway or pro-apoptotic Bim gene and initiates apoptosis. FoxO3a also induces the expression of cell cycle progression inhibitors including p27 and CyclinD1, thus stalling the G1/S phase transition . Here, we investigated whether the survival …

Cst foxo3a

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WebNov 15, 2016 · Besides, FoxO3a can trigger apoptosis by promoting the expressions of death receptor ligands in the extrinsic apoptotic pathway, such as Fas ligand 33 and tumor-necrosis-factor-related apoptosis ... WebMany studies have demonstrated that FoxO3a can bind to the promoter of Bim. Bim is a pro-apoptotic protein, initiating apoptosis mediated by mitochondria. Search. Target Antibody Protein Clone ELISA Kit; ... 301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday) Email [email protected] Address. 7505 Fannin St Ste 610-322 Houston ...

WebFeb 14, 2024 · The transcription factor FoxO3A is a key determinant of cancer cell homeostasis, playing a dual role in survival/death response to metabolic stress and cancer therapeutics. We recently described a novel mitochondrial arm of the AMPK-FoxO3A axis in normal cells upon nutrient shortage. WebDirections for Use: CST recommends transfection with 100 nM FoxO3a siRNA I 48 to 72 hours prior to cell lysis. For transfection procedure, follow protocol provided by the transfection reagent manufacturer. Please feel free to …

Web销售进口SIGMA试剂、abcam抗体、R&D抗体、CST抗体、ATCC细胞、BD公司、GE公司产品。 公司客户遍布大学、研究所、医院、卫生、商品检验检疫、制药公司、生物技术公司和食品工业等单位。 Web56484 Ensembl ENSG00000118689 ENSMUSG00000048756 UniProt O43524 Q9WVH4 RefSeq (mRNA) NM_001455 NM_201559 NM_019740 NM_001376967 RefSeq (protein) NP_001446 NP_963853 NP_062714 NP_001363896 Location (UCSC) Chr 6: 108.56 – 108.68 Mb Chr 10: 42.06 – 42.15 Mb PubMed search Wikidata View/Edit Human …

WebJan 1, 2012 · Doxorubicn treatment induces p38 MAPK activity and FOXO3a nuclear accumulation in MCF-7 breast carcinoma cell line. A, MCF-7 cells were treated with 1 μmol/liter of doxorubicin for 0, 1, 2, 4, 8, 16, and 24 h. At the indicated time, the cells were collected and analyzed by Western blotting using the antibodies indicated.

WebMonoclonal Antibody for studying FoxO3a. Cited in 446 publications. Validated for WB, IP, IF. Highly specific and rigorously validated in-house, FoxO3a (75D8) Rabbit Monoclonal … philosophy qvc on airWeb(12829) FoxO3a (D19A7) Rabbit mAb - Cell Signaling Technology - CiteAb 194 citations – A rabbit monoclonal antibody, raised against Forkhead box protein O3 (Human), supplied … t shirt printing centerWebSep 25, 2024 · The protein stability of FOXO3A is regulated by Casein Kinase 1 alpha (CK1α) in an oncogenic RAS-specific manner, but whether this mode of regulation extends to related FOXO family members is ... t shirt printing cedar hill txWeb豆丁网是面向全球的中文社会化阅读分享平台，拥有商业,教育,研究报告,行业资料,学术论文,认证考试,星座,心理学等数亿实用 ... t shirt printing caymanphilosophy quotes goodreadsWebFeb 18, 2024 · Previous evidence showed that the SIRT3–FOXO3a axis was a tumor suppressor in many cancers 42-44 it influenced EMT, 45 proliferation 46 and apoptosis. 47 Here, we confirmed that Adjudin activated the SIRT3–FOXO3a axis in SCLC, and the anticancer effect of Adjudin can be influenced by the expression levels of SIRT3 and … philosophy quotes on beautyWebApr 19, 2024 · The primary antibodies used in this study were AKT (1:1000; total and Ser473, Cell Signaling Technology Inc., Danvers, MA, USA), TOR (1:2000; total and Ser2448, CST), S6K1 (1:2000; total and Thr421/Ser424, CST), FOXO3a (1:3000; total and Ser253, Abcam, Cambridge, MA, USA), MAFBX and MURF-1 (1:4000; Zen … philosophy quotes about self